The principle of selective thermolysis can be applied towards the removal of tattoos. The energy delivered by a number of different lasers is targeted towards the carbon particles or dyes that are found in skin tattoos, allowing selective destruction of the foreign pigment while minimizing damage to the surrounding skin.

Lasers may be used on professional, amateur, cosmetic, medicinal, and traumatic tattoos. The different colors present in the tattoos may respond differently to laser tattoo removal. Lasers offer a non-invasive and effective treatment for unwanted tattoos.